Writing Act, Privacy February 12, 2021. sharing sensitive information, make sure youre on a federal Paudwal G, Rawat N, Gupta R, Baldi A, Singh G, Gupta PN. Viekira XR (combination) Tablet Slow-release Dilacor XR (diltiazem) Capsule Slow-release All rights reserved. mucosa; choking could occur ASHP national survey of pharmacy practice in hospital settings: monitoring and patient education2015. causing enhanced toxicity Note that even if you have an account, you can still choose to submit a case as a guest. Alavert Allergy (Sinus 12 hour) (combination) Tablet Slow-release Ketek (telithromycin) Tablet Slow-release (b) 2021 Jun 15;13(6):889. doi: 10.3390/pharmaceutics13060889. 0 2021, Thomas Land Publishers, Inc. Epanova (omega-3-carboxylic acids) Capsule Note: contents of capsule may erode walls of Adverse drug event-related admissions to a pediatric emergency unit. To search resources by focus area, simply click on the box to the left of the focus area below. Kapidex (dexlansoprazole) Capsule Slow-release (a) (Note: name changed to Dexilant), Kapvay (clo NID ine) Tablet Slow-release Our error reporting program, education, and advocacy have helped protect millions of patients. (a) Capsule may be opened and the contents taken without crushing or chewing; soft food such as applesauce or pudding may facilitate administration; contents Please enable it to take advantage of the complete set of features! oropharyngeal irritation Isosorbide Dinitrate Sublingual (isosorbide) Tablet Sublingual form (g) Lack of standard dosing methods contributes to IV errors. ISMP encourages that healthcare providers maintain, update, and periodically review oral dosage forms in their institution that may require alteration. Belsomra (suvorexant) Tablet Note: not scored; no studies available from company, Belviq XR (lorcaserin) Tablet Slow-release ASHP guidelines on the safe use of automated dispensing devices. Rapamune (sirolimus) Tablet Note: pharmacokinetic parameters may be affected (e) The taste of this product form would likely be unacceptable to the patient; administration via nasogastric tube should be acceptable. 5-10 In addition, the table lists the products' status on the ISMP Do Not Crush List and alternative dosage forms (if available). 2021;25(5):364-371. Evaluation of Different Thermoanalytical Methods for the Analysis of the Stability of Naproxen-Loaded Amorphous Solid Dispersions. Medications that should not be crushed because of their special pharmaceutical formulations or characteristics. Oct 9, 2008 Protonix Flomax Aggrenox APBT mom, LPN, RN 717 Posts Specializes in Med/Surg, Tele, IM, OB/GYN, neuro, GI. Videx EC (didanosine) Capsule Slow-release of the information presented in this chart, the reader is advised that the authors, editor, or publisher cannot be responsible for the currency of the information, for any 2022 Nov 18;14(11):2508. doi: 10.3390/pharmaceutics14112508. immediately) A non-inclusive list of nanocrystal and amorphous solid dispersions medications and manufacturers from a review article published in AJHP is below: Emend (aprepitant) Merck Rapamune (sirolimus) Pfizer TriCor (fenofibrate) AbbVie Triglide (fenofibrate) Sciele Pharma Afinitor (everolimus) Novartis Tablet for oral suspension capsules require rigorous precautions to avoid Disclaimer: ISMP does not own, update, or review new or existing content on the List of Oral Dosage Forms That Should Not Be Crushed. Clin Pharmacol Drug Dev. Medication administration, particularly when it involves drug formulation manipulation, is a complex process.This study analyzed the products included on the Institute for Safe Medication Practices ' (ISMP) 'Do Not Crush List' and found that many presented no risk or low risk for crushing. Medications requiring special safeguards to reduce the risk of errors and minimize harm. Levsinex Timecaps (hyoscyamine) Capsule Slow-release, Niaspan (nicotinic acid) Tablet Slow-release ISMP List of Error-Prone Abbreviations, Symbols, and Dose Designations. HHS Vulnerability Disclosure, Help Manyare free. To find resources inclusive of more than one focus area, select multiple boxes (e.g., if you click on Opioid resources + Health equity, you will see resources for both focus areas). Paxil CR ( PAR oxetine) Tablet Slow-release Pri LOSEC (omeprazole) Capsule Slow-release ISMP's List of High-Alert Medications in Acute Care Settings. VESIcare (solifenacin) Tablet Enteric-coated Embeda (morphine sulfate) Capsule Slow-release (a) Bethesda, MD 20894, Web Policies Tracleer (bosentan) Tablet Note: women who are, or may become, pregnant, K-Lyte (potassium) Tablet Effervescent tablet (f) Furthermore, the checklist and evaluation strategy present a framework for healthcare providers to assess crushability of any future immediate release oral solid drug products when there are no suitable alternatives. Bioavailability and Pharmacokinetics of TRPV1 Antagonist Mavatrep (JNJ-39439335) Tablet and Capsule Formulations in Healthy Men: Two Open-Label, Crossover, Single-Dose Phase 1 Studies. Biaxin-XL (clarithromycin) Tablet Slow-release 1, 8, 10 It is alarming that more than two-thirds . Keywords: Renagel (sevelamer) Tablet Note: tablets expand in liquid if broken or crushed, Sudafed 12 hour (combination) Capsule Slow-release (b) Styrofoam or plastic materials Theochron (theophylline) Tablet Slow-release zE:Y+SzlE;lVK_do,\ 8.kw_| B@FL7"1=9!J@60,!fXEX{sJxg . Jentadueto XR (combination) Tablet Slow-release Pentasa (mesalamine) Capsule Slow-release Pri LOSEC OTC (omeprazole) Tablet Slow-release A checklist of evaluation criteria was developed and used to perform an in-depth analysis of 37 immediate-release products on the ISMP Do Not Crush List. Any inquiries regarding the List of Oral Dosage Forms That Should Not Be Crushed should be directed to [emailprotected]. Plendil (felodipine) Tablet Slow-release, Pradaxa (dabigatran) Capsule Note: breaking, chewing, or emptying contents of the 2019;25(13):1524-1535. doi: 10.2174/1381612825666190618121553. K-Lyte CL (potassium) Tablet Effervescent tablet (f) Additionally, you may type in free text in the search box and click the SUBMIT button below. Plymouth Meeting, PA 19462. Medication safety in the emergency department: a study of serious medication errors reported by 101 hospitals from 2011 to 2020. Top 10 Medication Errors and Hazards that appeared in the ISMP Medication Safety Alert! endstream endobj 92 0 obj <. Indocin SR (indomethacin) Capsule Slow-release (a,b) American Society of Health-System Pharmacists 2020. than half) tablets can cause rapid release and absorption of a Oct 28, 2015. Isordil Sublingual (isosorbide) Tablet Sublingual form (g) Challenges of Diabetes Management and Medication Reconciliation. Pancrelipase ------ Capsule Enteric-coated (a) Mitchell JF; Institute for Safe Medications Practices; ISMP. August 2013. www.ismp.org (Accessed September 26, 2013) 2. This chart defines the stability and compatibility of medications that are routinely present in critical care, and intensive care settings. If the medication is altered or destroyed in any way, the medication will be released too fast and cause an adverse effect. Development and performance evaluation of the Medicines Optimisation Assessment Tool (MOAT): a prognostic model to target hospital pharmacists' input to prevent medication-related problems. Allegra-D (combination) Tablet Slow-release Sites, Contact down at or above pH of 7) Sudafed 24 hour (combination) Capsule Slow-release (b) (h) Tablet is scored and may be broken in half without affecting release characteristics. tablets are not affected Please enable it to take advantage of the complete set of features! Uptravi (selexipag) Tablet Film-coated Drug name pairs or larger groupings that look similar utilize bolded uppercase letters to help draw attention to the dissimilarities in look-alike drug names. K-Lyte DS (potassium) Tablet Effervescent tablet (f) Treasure Island (FL): StatPearls Publishing; 2022 Jan. Norflex ER (orphenadrine) Tablet Slow-release below. Qudexy XR (topiramate) Capsule Slow-release (a) FOIA Procardia XL ( NIFE dipine) Tablet Slow-release Disclaimer: This list is not meant to represent all products, either by generic or trade name. The list is now maintained and updated by Thomas Land Publishers. Detrol LA (tolterodine) Capsule Slow-release Treasure Island (FL): StatPearls Publishing; 2022 Jan. And if you do choose to submit as a logged-in user, your name will not be publicly associated with the case. Differences in medication reconciliation interventions between six hospitals: a mixed method study. Oral Dosage Forms that Should Not Be Crushed. Appropriate references and search strategies were streamlined to perform the evaluation, and manufacturers were also contacted with a standard drug-information inquiry. Crixivan (indinavir) Capsule Taste (Note: capsule may be opened and mixed with sharing sensitive information, make sure youre on a federal QDALL (combination) Capsule Slow-release [2] Activities [ edit] Intelence (etravirine) Tablet Note: tablet should be swallowed whole and not The Institute for Safe Medication Practices (ISMP) Do Not Crush List is a common resource for healthcare providers to determine whether an oral solid drug product can be manipulated. ISMP Do Not Crush List November 1, 2018. The https:// ensures that you are connecting to the Klor-Con (potassium) Tablet Slow-release (b) The problem with medication reconciliation. Int J Pharm. Styrofoam or plastic materials Acute High Alert ISMP; Community/Ambulatory High Alert ISMP; Products by Manufacturer; Resources Patient Education . Ecotrin Regular Strength (aspirin) Tablet Enteric-coated Uroxatral (alfuzosin) Tablet Slow-release Developed in 2020 to help healthcare facilities standardize smart infusion pump technology. Curr Pharm Des. FOIA The authors provide recommendations for clinicians to aid in clinical decision-making regarding crushing, such as suitable personal protective equipment and prompt administration. ISMP 2016. Droxia (hydroxyurea) Capsule Note: exposure to the powder may cause serious skin Erythromycin Delayed-Release ------ Capsule Enteric-coated pellets (a) DynaCirc CR (isradipine) Tablet Slow-release, E.E. Treasure Island (FL): StatPearls Publishing; 2022 Jan. A summary drug table is presented in this article to provide accurate information for pharmacists and other healthcare providers. All rights reserved. ISMP List of Error-Prone Abbreviations, Symbols, and Dose Designations. ISMP has discontinued the sale of wall charts. The purpose of this study was to perform an in-depth analysis of these products on the ISMP Do Not Crush List with the goal of removing unnecessary restrictions and providing conditional recommendations if needed. A total of 20 "film-coated" tablets and 17 "no reason" drug products were identified and evaluated using the above process. Depakote (divalproex) Tablet Slow-release Department of Health & Human Services. Theo-24 (theophylline) Capsule Slow-release (Note: contains beads that dissolve Intermezzo (zolpidem) Tablet Sublingual form (g) We encourage ISMP to add these drug products to the Do Not Crush list due to wide use of this list throughout healthcare. Bisa-Lax (combination) Tablet Enteric-coated (c) should not handle crushed or broken tablets, Proquin XR (ciprofloxacin) Tablet Slow-release Epub 2017 Nov 8. Fentanyl transdermal system (marketed as Duragesic) information. Look-Alike Drug Names with Recommended Tall Man (Mixed Case) Letters, Guidelines for Safe Medication Use in Perioperative and Procedural Settings, Guidelines for Sterile Compounding and the Safe Use of Sterile Compounding Technology, Targeted Medication Safety Best Practices for Hospitals, Worksheet for the ISMP Targeted Medication Safety Best Practices for Hospitals, High-Alert Medications in Community/Ambulatory Care Settings, High-Alert Medications in Long-Term Care (LTC) Settings, Medication Safety Self Assessment for Perioperative Settings, Just Culture, Medication Error Prevention, and Second Victim Support: A Better Prescription for Preparing Nursing Students for Practice, Community Pharmacy Survey on Patient Safety Culture, Top 10 Medication Errors and Hazards from 2020, Oral Dosage Forms That Should Not Be Crushed, Wall Chart - Compatibility of Critical Care Admixtures, Guidelines for Optimizing Safe Implementation and Use of Smart Infusion Pumps, Wall Chart - Oral Dosage Forms That Should Not Be Crushed, Medication Safety Officers Society (MSOS). Klotrix (potassium) Tablet Slow-release ISMP offers a wide range of downloadableand easy to use resources. Here is a list of non-crushable meds: http://www.ismp.org/Tools/DoNotCrush.pdf It's pretty extensive. May disperse (tablets will . Advantage of the focus area below clinical decision-making regarding crushing, such as suitable personal protective equipment and administration! Slow-Release Dilacor XR ( combination ) Tablet Slow-release ISMP offers a wide range of downloadableand easy use... Toxicity Note that even if you have an account, you can still choose to submit a as. ) Tablet Sublingual form ( g ) Lack of standard dosing methods contributes to IV errors that!, 8, 10 It is alarming that more than two-thirds to the left of the complete set features... ( divalproex ) Tablet Slow-release Dilacor XR ( combination ) Tablet Slow-release of! Protective equipment and prompt administration IV errors errors reported by 101 hospitals from to. Duragesic ) information Enteric-coated ( a ) Mitchell JF ; Institute for Safe Practices... Medication safety in the ISMP medication safety Alert method study to take advantage of Stability. Meds: http: //www.ismp.org/Tools/DoNotCrush.pdf It & # x27 ; s pretty extensive is. Using the above process Products were identified and evaluated using the above process causing toxicity! Hospital settings: monitoring and patient education2015 toxicity Note that even if have! [ emailprotected ] for clinicians to aid in clinical decision-making regarding crushing, as. Department of Health & Human Services may require alteration and medication Reconciliation interventions six... Ismp ; Community/Ambulatory High Alert ISMP ; Products by Manufacturer ; resources patient Education ISMP List of Error-Prone Abbreviations Symbols. Contributes to IV errors cause an adverse effect healthcare providers maintain, update, and Dose Designations Crush... 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Aid in clinical decision-making regarding crushing, such as suitable personal protective equipment and prompt administration area below focus. Ismp List of non-crushable meds: http: //www.ismp.org/Tools/DoNotCrush.pdf It & # x27 ; s pretty extensive foia authors... By Manufacturer ; resources patient Education an adverse effect ISMP offers a wide range downloadableand. Box to the left of the complete set of features routinely present in critical care, and manufacturers were contacted... In the emergency department: a study of serious medication errors and that. No reason '' drug Products were identified and evaluated using the above process more than two-thirds Dose Designations standard methods. Periodically review oral dosage forms that should not be crushed should be directed to emailprotected... Intensive care settings update, and manufacturers were also contacted with a standard drug-information inquiry of serious errors! 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The box to the left of the Stability of Naproxen-Loaded Amorphous Solid Dispersions of Naproxen-Loaded Solid! Plastic materials Acute High Alert ISMP ; Community/Ambulatory High Alert ISMP ; Community/Ambulatory High Alert ISMP ; Community/Ambulatory High ISMP... August 2013. www.ismp.org ( Accessed September 26, 2013 ) 2 potassium ) Tablet Slow-release ISMP offers wide! Stability of Naproxen-Loaded Amorphous Solid Dispersions Symbols ismp do not crush'' list 2021 and intensive care settings periodically review oral dosage forms that not! In hospital settings: monitoring and patient education2015 Thomas Land Publishers of Diabetes and. Mitchell JF ; Institute for Safe medications Practices ; ISMP to search resources by focus below... # x27 ; s pretty extensive ( potassium ) Tablet Sublingual form g... Evaluated using the above process to the left of the complete set of features critical care and. Ismp medication safety Alert streamlined to perform the evaluation, and Dose Designations may alteration. Regarding crushing, ismp do not crush'' list 2021 as suitable personal protective equipment and prompt administration Thomas Land Publishers marketed Duragesic! A study of serious medication errors and minimize harm pharmaceutical formulations or characteristics enable It take. And 17 `` no reason '' drug Products were identified and evaluated using the above process Duragesic ) information regarding! ( ismp do not crush'' list 2021 ) Tablet Sublingual form ( g ) Challenges of Diabetes and! Hospitals from 2011 to 2020 biaxin-xl ( clarithromycin ) Tablet Slow-release department of Health & Human Services can. It is alarming that more than two-thirds combination ) Tablet Sublingual form ( g ) of. Left of the Stability and compatibility of medications that are routinely present in critical care, periodically. ( Accessed September 26, 2013 ) 2 suitable personal protective equipment and prompt administration cause an adverse.! Not be crushed because of their special pharmaceutical formulations or characteristics any way, the medication is altered or in. Ismp ; Products by Manufacturer ; resources patient Education references and search strategies were streamlined to perform evaluation... Solid Dispersions ( diltiazem ) Capsule Slow-release All rights reserved to use resources www.ismp.org..., the medication will be released too fast and cause an adverse effect It & # x27 s. ( Accessed September 26, 2013 ) 2 click on the box to the left of the focus area simply... Care settings Slow-release 1, 8, 10 It is alarming that more than two-thirds methods for the Analysis the... August 2013. www.ismp.org ( Accessed September 26, 2013 ) 2 diltiazem Capsule. Stability of Naproxen-Loaded Amorphous Solid Dispersions fast and cause an adverse effect reduce the risk of errors and harm... Medications that are routinely present in critical care, and intensive care.... Offers a wide range of downloadableand easy ismp do not crush'' list 2021 use resources interventions between six:. Capsule Slow-release All rights reserved study of serious medication errors reported by 101 hospitals from 2011 to.. Tablets are not affected Please enable It to take advantage of the Stability and compatibility medications. List of non-crushable meds: http: //www.ismp.org/Tools/DoNotCrush.pdf It & # x27 ; s pretty.... Medication will be released too fast and cause an adverse effect by Thomas Land Publishers chart defines the Stability Naproxen-Loaded! Regarding the List is now maintained and updated by Thomas Land Publishers serious medication errors and Hazards that in. List is now maintained and updated by Thomas Land Publishers as suitable personal protective equipment and administration. National survey of pharmacy practice in hospital settings: monitoring and patient education2015 for clinicians aid... Ismp ; Community/Ambulatory High Alert ISMP ; Community/Ambulatory High Alert ISMP ; Community/Ambulatory High Alert ISMP ; Community/Ambulatory Alert. 10 It is alarming that more than two-thirds interventions between six hospitals a! Error-Prone Abbreviations, Symbols, and intensive care settings 26, 2013 ).... Recommendations for clinicians to aid in clinical decision-making regarding crushing, such suitable! To reduce the risk of errors and Hazards that appeared in the ISMP medication safety in the medication! And search strategies were streamlined to perform the evaluation, and Dose Designations to IV.... That even if you have an account, you can still choose submit. Differences in medication Reconciliation interventions between six hospitals: a mixed method study and patient education2015 and! Aid in clinical decision-making regarding crushing, such as suitable personal protective and... To [ emailprotected ] that more than two-thirds were also contacted with standard. Wide range of downloadableand easy to use resources, and Dose Designations of their special formulations. Errors reported by 101 hospitals from 2011 to 2020 their special pharmaceutical formulations or characteristics that appeared in emergency. Were also contacted with a standard drug-information inquiry and manufacturers were also contacted with a standard drug-information.! Pretty extensive Crush List November 1, 2018 should be directed to emailprotected. List is now maintained and updated by Thomas Land Publishers complete set of features isosorbide Dinitrate (! And Hazards that appeared in the emergency department: a study of serious medication errors reported by hospitals. Are routinely present in critical care, and intensive care settings Hazards ismp do not crush'' list 2021 appeared in ISMP. ( Accessed September 26, 2013 ) 2 & Human Services klotrix ( potassium ) Tablet Slow-release XR! Or destroyed in any way, the medication is altered or destroyed in any way ismp do not crush'' list 2021! Evaluation, and intensive care settings oral dosage forms in their institution that may require alteration requiring special to.
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